Lyophilizer Basic Multi-Manifolds

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Lypholizers or Freeze Dryers from Bio Gene helps your bio sensitive products such as enzymes, hormones, vaccines, antibiotics, milk etc to get well preserved for a long duration and again return to their original state once the water content  is reached to desired composition, thereby no losses of biochemical properties are observed. 

Removing of moisture content under vacuum from the frozen samples enables the dehydration which leads to sublimation and Lypholization.

BioGene Lypholizer Freeze dryers thus ensures water free Lypholized material.

These Lypholizer Are available from 1.0 Ltr -10.0 Ltrs capacity is under -40°C -70°C and -86°C temperatures. Operator friendly attachments for tubes, vials, flask in multi manifold, Pre freeze drying cabinet for large volume samples with press for squeeze and fast lypholizing is our standard design.

Bio Gene cares for its Lypholizer Research scientist therefore we ensure proper training and documentation to establish the process capabilities.

All these lead to make by BioGene a leading Lypholizer Freeze Dryer machine manufacturer all over the world.

  • Applications
  • Features
  • Control
  • Construction
  • Specification
  • Bio Gene introduces Novel and compact design for table top vacuum freeze Drying Lyophization Technique with Dedicated Human Machine Interface.
  • Advance Freeze & Drying process Analysis Software enable direct interface with in process controls to make desired changes. 
  • Touch screen 7” control system with true colour.
  • Touch LCD for display of set up and operating parameters in Graphic bar & Curve depicture.
  • Bio Gene HMI controller has inbuilt large storage memory capable to store 32 program cycles of 36 segments in each programs. Auto correction of program data on computing. Capability to memorize desired correct freez drying cuvees and than analysize the machine performance no key control panel direct software library recall.
  • Live freeze drying process observation.
  • One button auto start-up automatic operation to the drying mode. 
  • Big open stainless steel collector with pre-freeze function 
  • Transparent drying chamber is robust and convenient.
  • Stainless steel shelves. Space between adjustable (no screw cover type) 
  • Bio Gene® Lyophilizer cryo generator uses with HCFC/CFC-free with high repute Danfoss unit.
  • Compressor, High condenser capacity, Automatic defrosts.
  • Rapid cold Trap function at low Temperature. 
  • Ultra low condenser temperatures for processing a full range of samples (-55ºc + 5°C) or -800C +50C
  • Vacuum pump with oil mist filters with ultimate vacuum 2 X 10-3 mbar with displacement capacity of minimum 100L/min, 220/230 V and 50 Hz.
  • International KF Fast connector.
  • Run Program Graphics Log & Curves storage
  • USB Port for data trandfer & Printing.
  • Green environmental CFC friendly
  • Interface, display drying curve and history curve;
  • U disk Can storage lyophilized data;
  • Upload software can print process data in Graphics as well.
  • Embedded circuit design, 128 M FLASH, 
  • can save dozen times Lyophilized data.
  • Large opening trap, no coil inside
  • Samples pre-freeze function
  • Imported CRYO Generator from Danfoss.
  • Cold trap and control panel made of stainless steel, corrosion-resistant, easy to clean
  • Transparent Bell type drying room, secure and ocular
  • Stainless steel sample holder, common sample plate spacing adjustable
  • Small size and easy to operate
  • Nitrogen inflation valve.

CONTROL SYSTEM OPERATION

Bio Gene machine control system uses a 7-inch TFT LCD touch screen display, which is the Human-Machine Interface. The device is easy to operate, running status can be also clearly observed on display TFT. The system is able to use curve to show the sample temperature, the temperature of the cold trap, and the degree of vacuum freeze-drying curve. The Lyophilizer uses a variety of stability measures, control system operation is stable and reliable. Over temperature protection and precisely tuned heating technology.Adjustment of pre-heated fresh air admixture by air flap control in 10 % steps.

  • Advance freeze & Drying process Analysis software enable direct interface with in process controls to make desired changes. 
  • Touch screen 7” control system with true colour.
  • Touch LCD for display of set up and operating parameters in Graphic bar & Curve depicture.
  • Bio Gene HMI controller has inbuilt large storage memory capable to store 32 program cycles of 36 segments in each programs.
  • Auto correction of program data on computing. Capability to memorize desired correct freez drying cuvees and than analysize the machine performance no key control panel direct software library recall. 

OVER TEMPERATURE PROTECTION

  • Adjustable Electronic Over temperature monitor and mechanical temperature limiter TB, protection class 1 according to DIN 12880 to switch off the heating approx. 20°C above nominal temperature 2-point locking for freeze & vacuum.
  • Easy-to-clean interior, made of stainless steel, reinforced by deep drawn ribbing with integrated and protected large-area heating on all sides.
  • Temp range: RT + 5 to -50°C/-86°C with LCD/LED TFT display. Over temperature safety protection and over current protection and air ventilation.
  • Calibration facility directly at Control Panel/ Cockpit for three freely selectable temperature values. 1 Pt100 sensor DIN class A in 4-wire-circuit.
  • Set point wait function - the process time does not start until the set temperature is reached.
  • Resolution of display for set point values 0.1°C up to 99.9°C, 0.5°C from 100°C and for actual values 0.1°C (LED) Programmed stored in case of  power failure.

VACUUM 

RAPID VACUUM

Vacuum pump with oil mist filters with ultimate vacuum 2 X 10-3 mbar with displacement capacity of minimum 100L/min, 220/230 V and 50 Hz.
Rapid Vacuum to produce quick temperature equilibration and recovery, when needed Receptacles, in-chamber, moisture –proof  receptacle  IN Top Press chamber & sample trays & in the Multi pipeline for micro tubes or flasks.

 

Bio Gene Lyophilizer is Double walled construction and stainless steel AISI 304 grade steel. Made of high-quality, hygienic, easy-to-clean stainless steel machine with advance technology,

THE INNER COLD TRAP CHAMBER Bio Gene Lyopholizer is made of heavy gauge stainless steel sheet of SS-304 grade.

PRE FREEZE CHAMBER

Bell Type made transparent Plexi Glass Cylindrical with corrosion resistant steel Trays to view in process lyophilizing.

OUTER BODY of our Bio Gene Lyopholizer constructed out of Textures Stainless Steel Casing with powder coating.

The unit is provided with Double level fast freeze drying control of Stain less steel (1mm thick) with CNC press punched back panel for internal efficient Temperature and vacuum circulation.  The cold trap is provided with Gasket silicon. Aero dynamic internal design for achieving fast process results

CASTER WHEEL
Bio Gene  Lyopholizer  the unit is mounted on a sturdy steel frame and provided with castor wheels for easy movement inside the laboratory.

STEEL SHELVES:  Bio Gene  Lyopholizer  is supplied with 03 nos adjustable samples Trays fabricated from 304 grade SS sheets minimum 1.2 mm thick.

VENTILATION AND CONTROL
Vent connection with restrictor flap adaptive multifunctional digital PID microprocessor controller.

INSULATION
The gap between the walls is filled high-grade PUF, which ensures maximum thermal efficiency in our Bio Gene Lyopholizer with insulation of 50 mm.

MATRIX BTI-BMM-N10 BTI-BMM-N12 BTI-BMM-N18
No-load Temperature <-56℃ <-56℃ <-56℃
Freeze Area 0.12 m2 0.12 m2 0.18 m2
Plate Load Capacity 1.5 L 1.5 L 2 L
Ability to Capture Water 3 Kg 4Kg 6Kg
Vacuum Degree <10Pa <10Pa <10Pa
Machine Dimension W450×D580×H(380+450)mm W600×D460×H(720+450)mm W670×D530×H(800+450)mm
Sample Tray Size Ø 200 mm 4×Φ200mm 4×Φ240mm
Power 950W 950W 1300W
Power Supply 110V/60Hz or 220V/50Hz 110V/60Hz or 220V/50Hz 110V/60Hz or 220V/50Hz
interlayer spacing 70 mm 70 mm 70 mm
Cold trap size Ø215×160 mm Ø215×216 mm Ø270×410 mm
The number of
Flat bottom bottles
Ø22: 260
Ø16: 480
Ø12: 920
Ø22: 260
Ø16: 480
Ø12: 920
Ø22: 360
Ø16: 740
Ø12: 1320 
N.W./ G.W 95KG/110KG 120KG/135KG 135KG/150KG
Packing Size 1040*660*640mm 940*720*880 mm 760*1000*1040mm
An ISO 9001Certified EC, EU